Dopamine transporter imaging: nonindependence of regional measures
نویسندگان
چکیده
منابع مشابه
Molecular imaging of the dopamine transporter.
The dopamine transporter (DAT) is a transmembrane protein responsible for reuptake of dopamine from the synaptic cleft and termination of dopaminergic transmission. Several radioligands are available for DAT imaging with SPECT and PET. This review summarizes the main SPECT and PET radioligands and the main applications of DAT imaging in neuropsychiatric disorders.
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This article gives an update on nigrostriatal dopamine terminal imaging, with emphasis on SPECT performed with the presynaptic dopamine transporter (DAT) ligand (123)I-FP-CIT. The paper covers the rational use of this technique in the diagnostic work-up of patients with known or suspected parkinsonian syndromes. In detail, it addresses the impact of the method for the proof or exclusion of neur...
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[TOP] Dopamine transporter imaging with single photon emission computed tomography (DAT-SPECT) is investigational for all indications, including but not limited to: Aiding in the diagnosis of patients with clinically uncertain parkinsonian syndromes; OR Distinguishing between parkinsonian syndromes and essential tremor; OR Distinguishing between dementia with Lewy bodies and Alzheimer dis...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2014
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2014.15